Claudin 1 and nephrin label cellular crescents in diabetic glomerulosclerosis
نویسندگان
چکیده
منابع مشابه
Diabetic glomerulosclerosis.
I would like to show first the glomerulus of a 92-year-old man who did not have diabetes. It is perfectly normal. I want to emphasize that in the glomerulus there is not necessarily any ageing phenomenon per se. With the electron microscope there may be a slight increase in the thickness of the basement membrane of the glomerular capillary, but it is not visible by light microscopy. In the norm...
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Diabetic nephropathy is one of the leading causes of renal failure in Western countries, where diabetic patients account for nearly half of all patients on haemodialysis. Progressive expansion of the mesangial matrix, and thickening of the glomerular and tubular basement membranes without signs of major cell proliferation are hallmarks of human and experimental diabetic nephropathy. These lesio...
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ژورنال
عنوان ژورنال: Human Pathology
سال: 2014
ISSN: 0046-8177
DOI: 10.1016/j.humpath.2013.10.030